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Regional Differences in Brain-Derived Neurotrophic Factor Levels and Dendritic Spine Density Confer Resilience to Inescapable Stress

BACKGROUND: In the learned helplessness (LH) paradigm, approximately 35% of rats are resilient to inescapable stress. METHODS: The roles of brain-derived neurotrophic factor (BDNF) and dendritic spine density in the brain regions of LH (susceptible) and non-LH rats (resilient) were examined. Western...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Yang, Chun, Shirayama, Yukihiko, Zhang, Ji-chun, Ren, Qian, Hashimoto, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540100/
https://ncbi.nlm.nih.gov/pubmed/25568287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu121
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