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Rapid Analysis of Chromosome Aberrations in Mouse B Lymphocytes by PNA-FISH
Defective DNA repair leads to increased genomic instability, which is the root cause of mutations that lead to tumorigenesis. Analysis of the frequency and type of chromosome aberrations in different cell types allows defects in DNA repair pathways to be elucidated. Understanding mammalian DNA repai...
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| Vydáno v: | J Vis Exp |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MyJove Corporation
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4540087/ https://ncbi.nlm.nih.gov/pubmed/25177909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51806 |
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