Impact of in vitro evolution on antigenic diversity of Mycobacterium bovis bacillus Calmette-Guerin (BCG)

Mycobacterium bovis bacillus Calmette-Guerin (BCG), the only vaccine currently used against tuberculosis, is an attenuated derivative of M. bovis that has been propagated in vitro for more than 40 years. We have previously reported that the experimentally-verified human T cell epitopes of the M. tub...

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Bibliografiske detaljer
Udgivet i:Vaccine
Main Authors: Copin, Richard, Coscollá, Mireia, Efstathiadis, Efstratios, Gagneux, Sebastien, Ernst, Joel D.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539939/
https://ncbi.nlm.nih.gov/pubmed/25211768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.07.113
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