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Phenotype of Usher syndrome type II assosiated with compound missense mutations of c.721 C>T and c.1969 C>T in MYO7A in a Chinese Usher syndrome family

AIM: To identify the pathogenic mutations in a Chinese pedigree affected with Usher syndrome type II (USH2). METHODS: The ophthalmic examinations and audiometric tests were performed to ascertain the phenotype of the family. To detect the genetic defect, exons of 103 known RDs -associated genes incl...

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Détails bibliographiques
Publié dans:Int J Ophthalmol
Auteurs principaux: Zhai, Wei, Jin, Xin, Gong, Yan, Qu, Ling-Hui, Zhao, Chen, Li, Zhao-Hui
Format: Artigo
Langue:Inglês
Publié: International Journal of Ophthalmology Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539639/
https://ncbi.nlm.nih.gov/pubmed/26309859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3980/j.issn.2222-3959.2015.04.05
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