Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation

Inflammation drives atherosclerotic plaque progression and rupture, and is a compelling therapeutic target. Consequently, attenuating inflammation by reducing local macrophage accumulation is an appealing approach. This can potentially be accomplished by either blocking blood monocyte recruitment to...

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Veröffentlicht in:Sci Adv
Hauptverfasser: Tang, Jun, Lobatto, Mark E., Hassing, Laurien, van der Staay, Susanne, van Rijs, Sarian M., Calcagno, Claudia, Braza, Mounia S., Baxter, Samantha, Fay, Francois, Sanchez-Gaytan, Brenda L., Duivenvoorden, Raphaël, Sager, Hendrik B., Astudillo, Yaritzy M., Leong, Wei, Ramachandran, Sarayu, Storm, Gert, Pérez-Medina, Carlos, Reiner, Thomas, Cormode, David P., Strijkers, Gustav J., Stroes, Erik S. G., Swirski, Filip K., Nahrendorf, Matthias, Fisher, Edward A., Fayad, Zahi A., Mulder, Willem J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2015
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539616/
https://ncbi.nlm.nih.gov/pubmed/26295063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1400223
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