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A nuclear role for the respiratory enzyme CLK-1/COQ7 in regulating mitochondrial stress responses and longevity
The coordinated regulation of mitochondrial and nuclear activities is essential for cellular respiration and its disruption leads to mitochondrial dysfunction, a hallmark of ageing. Mitochondria communicate with nuclei via retrograde signalling pathways that modulate nuclear gene expression in order...
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| Yayımlandı: | Nat Cell Biol |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539581/ https://ncbi.nlm.nih.gov/pubmed/25961505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3170 |
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