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Retinoic acid signaling in B-cells is essential for oral immunization and microflora composition

Retinoic acid (RA)() is a critical regulator of the intestinal adaptive immune response. However, the intrinsic impact of RA on B cell differentiation in the regulation of gut humoral immunity in vivo has never been directly shown. To address this issue, we have been able to generate a mouse model w...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Pantazi, Eirini, Marks, Ellen, Stolarczyk, Emilie, Lycke, Nils, Noelle, Randolph J., Elgueta, Raul
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539572/
https://ncbi.nlm.nih.gov/pubmed/26163586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500989
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