Chemical intervention of the NM23-H2 transcriptional programme on c-MYC via a novel small molecule

c-MYC is an important oncogene that is considered as an effective target for anticancer therapy. Regulation of this gene's transcription is one avenue for c-MYC-targeting drug design. Direct binding to a transcription factor and generating the intervention of a transcriptional programme appears...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Shan, Chan, Lin, Jing, Hou, Jin-Qiang, Liu, Hui-Yun, Chen, Shuo-Bin, Chen, Ai-Chun, Ou, Tian-Miao, Tan, Jia-Heng, Li, Ding, Gu, Lian-Quan, Huang, Zhi-Shu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Chemical Biology and Nucleic Acid Chemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538829/
https://ncbi.nlm.nih.gov/pubmed/26117539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv641
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