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The AT-Hook motif as a versatile minor groove anchor for promoting DNA binding of transcription factor fragments
We report the development of chimeric DNA binding peptides comprising a DNA binding fragment of natural transcription factors (the basic region of a bZIP protein or a monomeric zinc finger module) and an AT-Hook peptide motif. The resulting peptide conjugates display high DNA affinity and excellent...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538796/ https://ncbi.nlm.nih.gov/pubmed/26290687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01415h |
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