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An Ancient Riboswitch Class in Bacteria Regulates Purine Biosynthesis and One-carbon Metabolism
Over thirty years ago, ZTP (5-amino-4-imidazole carboxamide riboside 5'-triphosphate), a modified purine biosynthetic intermediate, was proposed to signal 10-formyl-tetrahydrofolate (10f-THF) deficiency in bacteria. However, the mechanisms by which this putative alarmone or its precursor ZMP (5...
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| Gepubliceerd in: | Mol Cell |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538711/ https://ncbi.nlm.nih.gov/pubmed/25616067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.01.001 |
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