Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors

Although targeting cancer metabolism is a promising therapeutic strategy, clinical success will depend on an accurate diagnostic identification of tumor subtypes with specific metabolic requirements. Through broad metabolite profiling, we successfully identified three highly distinct metabolic subty...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Proc Natl Acad Sci U S A
मुख्य लेखकों: Daemen, Anneleen, Peterson, David, Sahu, Nisebita, McCord, Ron, Du, Xiangnan, Liu, Bonnie, Kowanetz, Katarzyna, Hong, Rebecca, Moffat, John, Gao, Min, Boudreau, Aaron, Mroue, Rana, Corson, Laura, O’Brien, Thomas, Qing, Jing, Sampath, Deepak, Merchant, Mark, Yauch, Robert, Manning, Gerard, Settleman, Jeffrey, Hatzivassiliou, Georgia, Evangelista, Marie
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2015
विषय:
PNAS Plus
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538616/
https://ncbi.nlm.nih.gov/pubmed/26216984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501605112
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