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Live-cell superresolution microscopy reveals the organization of RNA polymerase in the bacterial nucleoid

Despite the fundamental importance of transcription, a comprehensive analysis of RNA polymerase (RNAP) behavior and its role in the nucleoid organization in vivo is lacking. Here, we used superresolution microscopy to study the localization and dynamics of the transcription machinery and DNA in live...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Stracy, Mathew, Lesterlin, Christian, Garza de Leon, Federico, Uphoff, Stephan, Zawadzki, Pawel, Kapanidis, Achillefs N.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538611/
https://ncbi.nlm.nih.gov/pubmed/26224838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507592112
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