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Development of a Novel Real-Time PCR Assay with High-Resolution Melt Analysis To Detect and Differentiate OXA-48-Like β-Lactamases in Carbapenem-Resistant Enterobacteriaceae

The rapid global spread of carbapenem-resistant Enterobacteriaceae (CRE) poses an urgent threat to public health. More than 250 class D β-lactamases (OXAs) have been described in recent years, with variations in hydrolytic activity for β-lactams. The plasmid-borne OXA-48 β-lactamase and its variants...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Hemarajata, Peera, Yang, Shangxin, Hindler, Janet A., Humphries, Romney M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538549/
https://ncbi.nlm.nih.gov/pubmed/26124164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00425-15
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