Adequacy of High-Dose Cefepime Regimen in Febrile Neutropenic Patients with Hematological Malignancies

While guidelines recommend empirical cefepime therapy in febrile neutropenia, the mortality benefit of cefepime has been controversial. In light of this, recent reports on pharmacokinetic changes for several antibiotics in febrile neutropenia and the consequent suboptimal exposure call for a pharmac...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Sime, Fekade Bruck, Roberts, Michael S., Tiong, Ing Soo, Gardner, Julia H., Lehman, Sheila, Peake, Sandra L., Hahn, Uwe, Warner, Morgyn S., Roberts, Jason A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538521/
https://ncbi.nlm.nih.gov/pubmed/26124158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00389-15
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