Synergistic Effect of Membrane-Active Peptides Polymyxin B and Gramicidin S on Multidrug-Resistant Strains and Biofilms of Pseudomonas aeruginosa

Multidrug-resistant Pseudomonas aeruginosa is a major cause of severe hospital-acquired infections. Currently, polymyxin B (PMB) is a last-resort antibiotic for the treatment of infections caused by Gram-negative bacteria, despite its undesirable side effects. The delivery of drug combinations has b...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Berditsch, Marina, Jäger, Thomas, Strempel, Nikola, Schwartz, Thomas, Overhage, Jörg, Ulrich, Anne S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538509/
https://ncbi.nlm.nih.gov/pubmed/26077259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00682-15
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