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Sequential Chemoimmunotherapy of Experimental Visceral Leishmaniasis Using a Single Low Dose of Liposomal Amphotericin B and a Novel DNA Vaccine Candidate

Combination therapies for leishmaniasis, including drugs and immunomodulators, are one approach to shorten treatment courses and to improve the treatment of complex manifestations of the disease. We evaluated a novel T-cell-epitope-enriched DNA vaccine candidate (LEISHDNAVAX) as host-directed immuno...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Seifert, Karin, Juhls, Christiane, Salguero, Francisco J., Croft, Simon L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538505/
https://ncbi.nlm.nih.gov/pubmed/26055371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00273-15
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