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Sequential Chemoimmunotherapy of Experimental Visceral Leishmaniasis Using a Single Low Dose of Liposomal Amphotericin B and a Novel DNA Vaccine Candidate

Combination therapies for leishmaniasis, including drugs and immunomodulators, are one approach to shorten treatment courses and to improve the treatment of complex manifestations of the disease. We evaluated a novel T-cell-epitope-enriched DNA vaccine candidate (LEISHDNAVAX) as host-directed immuno...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Seifert, Karin, Juhls, Christiane, Salguero, Francisco J., Croft, Simon L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538505/
https://ncbi.nlm.nih.gov/pubmed/26055371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00273-15
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