Meropenem Population Pharmacokinetics in Critically Ill Patients with Septic Shock and Continuous Renal Replacement Therapy: Influence of Residual Diuresis on Dose Requirements

Meropenem dosing in critically ill patients with septic shock and continuous renal replacement therapy (CRRT) is complex, with the recommended maintenance doses being 500 mg to 1,000 mg every 8 h (q8h) to every 12 h. This multicenter study aimed to describe the pharmacokinetics (PKs) of meropenem in...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Ulldemolins, Marta, Soy, Dolors, Llaurado-Serra, Mireia, Vaquer, Sergi, Castro, Pedro, Rodríguez, Alejandro H., Pontes, Caridad, Calvo, Gonzalo, Torres, Antoni, Martín-Loeches, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538468/
https://ncbi.nlm.nih.gov/pubmed/26124172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00712-15
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