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Morphine disinhibits glutamatergic input to VTA dopamine neurons and promotes dopamine neuron excitation
One reported mechanism for morphine activation of dopamine (DA) neurons of the ventral tegmental area (VTA) is the disinhibition model of VTA-DA neurons. Morphine inhibits GABA inhibitory neurons, which shifts the balance between inhibitory and excitatory input to VTA-DA neurons in favor of excitati...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538365/ https://ncbi.nlm.nih.gov/pubmed/26208338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09275 |
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