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Systemic exposure to menthol following administration of peppermint oil to paediatric patients

OBJECTIVE: Peppermint oil (PMO) has been used to treat abdominal ailments dating to ancient Egypt, Greece and Rome. Despite its increasing paediatric use, as in irritable bowel syndrome (IBS) treatment, the pharmacokinetics (PK) of menthol in children given PMO has not been explored. DESIGN AND SETT...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Kearns, Gregory L, Chumpitazi, Bruno Pedro, Abdel-Rahman, Susan M, Garg, Uttam, Shulman, Robert J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538270/
https://ncbi.nlm.nih.gov/pubmed/26270949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-008375
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