Systemic exposure to menthol following administration of peppermint oil to paediatric patients

OBJECTIVE: Peppermint oil (PMO) has been used to treat abdominal ailments dating to ancient Egypt, Greece and Rome. Despite its increasing paediatric use, as in irritable bowel syndrome (IBS) treatment, the pharmacokinetics (PK) of menthol in children given PMO has not been explored. DESIGN AND SETT...

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Bibliographische Detailangaben
Veröffentlicht in:BMJ Open
Hauptverfasser: Kearns, Gregory L, Chumpitazi, Bruno Pedro, Abdel-Rahman, Susan M, Garg, Uttam, Shulman, Robert J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2015
Schlagworte:
Paediatrics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538270/
https://ncbi.nlm.nih.gov/pubmed/26270949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-008375
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