Systemic exposure to menthol following administration of peppermint oil to paediatric patients

OBJECTIVE: Peppermint oil (PMO) has been used to treat abdominal ailments dating to ancient Egypt, Greece and Rome. Despite its increasing paediatric use, as in irritable bowel syndrome (IBS) treatment, the pharmacokinetics (PK) of menthol in children given PMO has not been explored. DESIGN AND SETT...

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Publicat a:BMJ Open
Autors principals: Kearns, Gregory L, Chumpitazi, Bruno Pedro, Abdel-Rahman, Susan M, Garg, Uttam, Shulman, Robert J
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2015
Matèries:
Paediatrics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538270/
https://ncbi.nlm.nih.gov/pubmed/26270949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-008375
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