Heritability of liver enzyme levels estimated from genome-wide SNP data

Variation in the liver enzyme levels in humans is moderately heritable, as indicated by twin-family studies. At present, genome-wide association studies have traced <2% of the variance back to genome-wide significant single-nucleotide polymorphisms (SNPs). We estimated the SNP-based heritability...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: van Beek, Jenny H D A, Lubke, Gitta H, de Moor, Marleen H M, Willemsen, Gonneke, de Geus, Eco J C, Hottenga, Jouke Jan, Walters, Raymond K, Smit, Jan H, Penninx, Brenda W J H, Boomsma, Dorret I
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538200/
https://ncbi.nlm.nih.gov/pubmed/25424715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.259
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