Inflammation-induced abnormalities in the subcellular localization and trafficking of the neurokinin 1 receptor in the enteric nervous system

Activated G protein-coupled receptors traffic to endosomes and are sorted to recycling or degradative pathways. Endosomes are also a site of receptor signaling of sustained and pathophysiologically important processes, including inflammation. However, the mechanisms of endosomal sorting of receptors...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Gastrointest Liver Physiol
Main Authors: Poole, Daniel P., Lieu, TinaMarie, Pelayo, Juan Carlos, Eriksson, Emily M., Veldhuis, Nicholas A., Bunnett, Nigel W.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2015
Fag:
Neurogastroenterology and Motility
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537929/
https://ncbi.nlm.nih.gov/pubmed/26138465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00118.2015
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