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Modeling bipolar disorder in mice by increasing acetylcholine or dopamine: Chronic lithium treats most, but not all features

RATIONALE: Bipolar disorder (BD) is a disabling and life-threatening disease characterized by states of depression and mania. New and efficacious treatments have not been forthcoming partly due to a lack of well-validated models representing both facets of BD. OBJECTIVES: We hypothesized that cholin...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: van Enkhuizen, Jordy, Milienne-Petiot, Morgane, Geyer, Mark A., Young, Jared W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537820/
https://ncbi.nlm.nih.gov/pubmed/26141192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-4000-4
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