SDF-1/CXCR4 Axis Promotes MSCs to Repair Liver Injury Partially through Trans-Differentiation and Fusion with Hepatocytes

MSCs have become a popular target for developing end-stage liver therapies. In this study, two models of bone marrow chimeric mice were used to construct the liver failure models. Then it was found that MSCs can transdifferentiate into hepatocyte-like cells and these hepatocyte-like cells can signif...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Hao, Ning-Bo, Li, Chang-Zhu, Lü, Mu-Han, Tang, Bo, Wang, Su-Min, Wu, Yu-Yun, Liang, Guang-Ping, Yang, Shi-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537768/
https://ncbi.nlm.nih.gov/pubmed/26300925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/960387
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