Inhibition of Epithelial CC-Family Chemokine Synthesis by the Synthetic Chalcone DMPF-1 via Disruption of NF-κB Nuclear Translocation and Suppression of Experimental Asthma in Mice

Asthma is associated with increased pulmonary inflammation and airway hyperresponsiveness. The interaction between airway epithelium and inflammatory mediators plays a key role in the pathogenesis of asthma. In vitro studies evaluated the inhibitory effects of 3-(2,5-dimethoxyphenyl)-1-(5-methylfura...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Rajajendram, Revathee, Tham, Chau Ling, Akhtar, Mohamad Nadeem, Sulaiman, Mohd Roslan, Israf, Daud Ahmad
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537758/
https://ncbi.nlm.nih.gov/pubmed/26300589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/176926
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