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Transcription of a yeast telomere alleviates telomere position effect without affecting chromosome stability.

Telomeres are required for the stable maintenance of chromosomes in the yeast Saccharomyces cerevisiae. Telomeres also repress the expression of genes in their vicinity, a phenomenon known as telomere position effect. In an attempt to construct a conditional telomere, an inducible promoter was intro...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Sandell, L L, Gottschling, D E, Zakian, V A
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45376/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7991584/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.12061
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