Exenatide (a GLP-1 agonist) improves the antioxidative potential of in vitro cultured human monocytes/macrophages

Macrophages are dominant cells in the pathogenesis of atherosclerosis. They are also a major source of reactive oxygen species (ROS). Oxidative stress, which is particularly high in subjects with diabetes, is responsible for accelerated atherosclerosis. Novel antidiabetic drugs (e.g., glucagon-like...

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Bibliografske podrobnosti
izdano v:Naunyn Schmiedebergs Arch Pharmacol
Main Authors: Bułdak, Łukasz, Łabuzek, Krzysztof, Bułdak, Rafał Jakub, Machnik, Grzegorz, Bołdys, Aleksandra, Okopień, Bogusław
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2015
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537507/
https://ncbi.nlm.nih.gov/pubmed/25980358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-015-1124-3
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