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Differential effects of ghrelin antagonists on alcohol drinking and reinforcement in mouse and rat models of alcohol dependence

An effort has been mounted to understand the mechanisms of alcohol dependence in a way that may allow for greater efficacy in treatment. It has long been suggested that drugs of abuse seize fundamental reward pathways and disrupt homeostasis to produce compulsive drug seeking behaviors. Ghrelin, an...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Gomez, Juan L., Cunningham, Christopher L., Finn, Deborah A., Young, Emily A., Helpenstell, Lily K., Schuette, Lindsey M., Fidler, Tara L., Kosten, Therese A., Ryabinin, Andrey E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537402/
https://ncbi.nlm.nih.gov/pubmed/26051399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.05.026
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