Real-Time PCR Assays for the Quantification of HCV RNA: Concordance, Discrepancies and Implications for Response Guided Therapy

BACKGROUND AND AIMS: Monitoring of chronic Hepatitis C (CHC) treatment relies on HCV RNA quantification by means of real-time PCR methods. Assay specific analytical sensitivities may impact therapy management. METHODS: Comparative analysis between three commercial assays (Roche COBAS AmpliPrep/COBAS...

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Veröffentlicht in:PLoS One
Hauptverfasser: Strassl, Robert, Rutter, Karoline, Stättermayer, Albert Friedrich, Beinhardt, Sandra, Kammer, Michael, Hofer, Harald, Ferenci, Peter, Popow-Kraupp, Theresia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537232/
https://ncbi.nlm.nih.gov/pubmed/26274922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135963
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