Progressive Hemorrhage and Myotoxicity Induced by Echis carinatus Venom in Murine Model: Neutralization by Inhibitor Cocktail of N,N,N',N'-Tetrakis (2-Pyridylmethyl) Ethane-1,2-Diamine and Silymarin

Viperbite is often associated with severe local toxicity, including progressive hemorrhage and myotoxicity, persistent even after the administration of anti-snake venom (ASV). In the recent past, investigations have revealed the orchestrated actions of Zn(2+) metalloproteases (Zn(2+)MPs), phospholip...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nanjaraj Urs, Ankanahalli N., Ramakrishnan, Chandrasekaran, Joshi, Vikram, Suvilesh, Kanve Nagaraj, Veerabasappa Gowda, Teregowda, Velmurugan, Devadasan, Vishwanath, Bannikuppe Sannanaik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537139/
https://ncbi.nlm.nih.gov/pubmed/26274501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135843
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