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Heme Signaling Impacts Global Gene Expression, Immunity and Dengue Virus Infectivity in Aedes aegypti

Blood-feeding mosquitoes are exposed to high levels of heme, the product of hemoglobin degradation. Heme is a pro-oxidant that influences a variety of cellular processes. We performed a global analysis of heme-regulated Aedes aegypti (yellow fever mosquito) transcriptional changes to better understa...

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發表在:PLoS One
Main Authors: Bottino-Rojas, Vanessa, Talyuli, Octávio A. C., Jupatanakul, Natapong, Sim, Shuzhen, Dimopoulos, George, Venancio, Thiago M., Bahia, Ana C., Sorgine, Marcos H., Oliveira, Pedro L., Paiva-Silva, Gabriela O.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537099/
https://ncbi.nlm.nih.gov/pubmed/26275150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135985
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