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PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes
Genome-wide association study (GWAS) data showed that the protein tyrosine phosphatase receptor type delta (PTPRD) is associated with increased susceptibility to type 2 diabetes (T2D) in Han Chinese. A replication study indicated that PTPRD is involved in the insulin signaling pathway; however, the...
Kaydedildi:
| Yayımlandı: | Oncotarget |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Impact Journals LLC
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536994/ https://ncbi.nlm.nih.gov/pubmed/26079428 |
| Etiketler: |
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