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The Evolving Role of Chemical Synthesis in Antibacterial Drug Discovery

The discovery and implementation of antibiotics in the early twentieth century transformed human health and wellbeing. Chemical synthesis enabled the development of the first antibacterial substances, organoarsenicals and sulfa drugs, but these were soon outshone by a host of more powerful and vastl...

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Veröffentlicht in:Angew Chem Int Ed Engl
Hauptverfasser: Wright, Peter M., Seiple, Ian B., Myers, Andrew G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536949/
https://ncbi.nlm.nih.gov/pubmed/24990531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201310843
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