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Generation of monoclonal antibodies against MGA and comparison of their application in breast cancer detection by immunohistochemistry

Mammaglobin A (MGA) is an organ specific molecular biomarker for metastatic breast cancer diagnosis. However, there are still needs to develop optimal monoclonal antibodies (mAbs) to detect MGA expression in breast carcinoma by immunohistochemistry. In this study, we first generated mAbs against MGA...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Duan, Cuimi, Yang, Xiqin, Zhang, Xuhui, Feng, Jiannan, Liu, Zhiqiang, Que, Haiping, Johnson, Heather, Zhao, Yanfeng, Fan, Yawen, Lu, Yinglin, Zhang, Heqiu, Huang, Yan, Xiu, Bingshui, Feng, Xiaoyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536492/
https://ncbi.nlm.nih.gov/pubmed/26272389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13073
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