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Defects in Germinal Center Selection in SLE
Germinal centers (GCs) are the primary site at which clonal expansion and affinity maturation of B cells occur. B cells encounter antigen and receive T cell help in the GC light zone (LZ) and then migrate to the dark zone where they proliferate and undergo somatic mutation before cycling back to the...
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| Publicado en: | Front Immunol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536402/ https://ncbi.nlm.nih.gov/pubmed/26322049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00425 |
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