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Divergent target recognition by coexpressed 5′-isomiRs of miR-142-3p and selective viral mimicry

Sequence heterogeneity at the ends of mature microRNAs (miRNAs) is well documented, but its effects on miRNA function are largely unexplored. Here we studied the impact of miRNA 5′-heterogeneity, which affects the seed region critical for target recognition. Using the example of miR-142-3p, an emerg...

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Publicat a:RNA
Autors principals: Manzano, Mark, Forte, Eleonora, Raja, Archana N., Schipma, Matthew J., Gottwein, Eva
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536321/
https://ncbi.nlm.nih.gov/pubmed/26137849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.048876.114
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