Metazoan tRNA introns generate stable circular RNAs in vivo

We report the discovery of a class of abundant circular noncoding RNAs that are produced during metazoan tRNA splicing. These transcripts, termed tRNA intronic circular (tric)RNAs, are conserved features of animal transcriptomes. Biogenesis of tricRNAs requires anciently conserved tRNA sequence moti...

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Vydáno v:RNA
Hlavní autoři: Lu, Zhipeng, Filonov, Grigory S., Noto, John J., Schmidt, Casey A., Hatkevich, Talia L., Wen, Ying, Jaffrey, Samie R., Matera, A. Gregory
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536317/
https://ncbi.nlm.nih.gov/pubmed/26194134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.052944.115
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