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Regulation of GAP43/calmodulin complex formation via calcineurin-dependent mechanism in differentiated PC12 cells with altered PMCA isoforms composition

Several lines of evidence suggest the contribution of age-related decline in plasma membrane calcium pump (PMCA) to the onset of neurodegenerative diseases. From four PMCA isoforms, PMCA2, and PMCA3 respond to a rapid removal of Ca(2+) and are expressed predominantly in excitable cells. We have prev...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biochem
Hauptverfasser: Boczek, Tomasz, Ferenc, Bozena, Lisek, Malwina, Zylinska, Ludmila
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536269/
https://ncbi.nlm.nih.gov/pubmed/26045175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-015-2473-4
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