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Antidepressant-like cognitive and behavioral effects of acute ketamine administration associated with plasticity in the ventral hippocampus to medial prefrontal cortex pathway

RATIONALE: Acute low-dose administration of the NMDA receptor antagonist, ketamine, produces rapid and sustained antidepressant-like effects in humans and rodents. Recently, we found that the long-lasting effect of ketamine on the forced swim test requires ventral hippocampal (vHipp) activity at the...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Jett, Julianne D., Boley, Angela M., Girotti, Milena, Shah, Amiksha, Lodge, Daniel J., Morilak, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536154/
https://ncbi.nlm.nih.gov/pubmed/25986748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-3957-3
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