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Hox5 genes regulate the Wnt2/2b-Bmp4 signaling axis during lung development
Hox genes are required for proper anteroposterior axial patterning and the development of several organ systems. Herein, we show that all three Hox5 paralogous genes play redundant roles in the developing lung. Hoxa5;Hoxb5;Hoxc5 triple mutant embryos develop severely hypoplastic lungs with reduced b...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536095/ https://ncbi.nlm.nih.gov/pubmed/26235626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.07.020 |
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