Pulmonary Haemodynamics in Sickle Cell Disease Are Driven Predominantly by a High-Output State Rather Than Elevated Pulmonary Vascular Resistance: A Prospective 3-Dimensional Echocardiography/Doppler Study

AIMS: Patients with sickle cell disease have significant morbidity and mortality. Pulmonary hypertension is suggested to be an important contributor but its nature and severity in these patients and how best to non-invasively assess it are controversial. We hypothesised that a high-output state rath...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mushemi-Blake, Sitali, Melikian, Narbeh, Drasar, Emma, Bhan, Amit, Lunt, Alan, Desai, Sujal R., Greenough, Anne, Monaghan, Mark J., Thein, Swee Lay, Shah, Ajay M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535955/
https://ncbi.nlm.nih.gov/pubmed/26270484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135472
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