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The Expression of the Zonula Adhaerens Protein PLEKHA7 Is Strongly Decreased in High Grade Ductal and Lobular Breast Carcinomas

PLEKHA7 is a junctional protein, which participates in a complex that stabilizes E-cadherin at the zonula adhaerens. Since E-cadherin is involved in epithelial morphogenesis, signaling, and tumor progression, we explored PLEKHA7 expression in cancer. PLEKHA7 expression was assessed in invasive ducta...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Tille, Jean-Christophe, Ho, Liza, Shah, Jimit, Seyde, Olivia, McKee, Thomas A., Citi, Sandra
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535953/
https://ncbi.nlm.nih.gov/pubmed/26270346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135442
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