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Analysis of connexin expression during seizures induced by 4-aminopyridine in the rat hippocampus

BACKGROUND: In epilepsy, seizures are generated by abnormal synchronous activity in neurons. In the rat hippocampus (HIP), epileptiform activity has been found to be associated with gap junctions (GJs). GJs are formed by the combination of two hemichannels, each composed of six connexins. At low dos...

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Bibliographic Details
Published in:J Biomed Sci
Main Authors: Laura, Medina-Ceja, Xóchitl, Flores-Ponce, Anne, Santerre, Alberto, Morales-Villagrán
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535691/
https://ncbi.nlm.nih.gov/pubmed/26268619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0176-5
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