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Genome-wide binding of transcription factors in inv(16) acute myeloid leukemia

The inv(16) translocation is associated with 5% of AML cases and gives rise to expression of the oncofusion protein CBFβ-MYH11. Although different molecular mechanisms for the oncogenic activity of this fusion protein have been proposed these were mostly based on in vitro experiments or single loci...

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Publicat a:Genom Data
Autors principals: Mandoli, A., Prange, K., Martens, J.H.A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535528/
https://ncbi.nlm.nih.gov/pubmed/26484088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gdata.2014.06.014
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