A histone H3K36 chromatin switch coordinates DNA double-strand break repair pathway choice

DNA double-strand break (DSB) repair is a highly regulated process performed predominantly by non-homologous end joining (NHEJ) or homologous recombination (HR) pathways. How these pathways are coordinated in the context of chromatin is unclear. Here we uncover a role for histone H3K36 modification...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Pai, Chen-Chun, Deegan, Rachel S., Subramanian, Lakxmi, Gal, Csenge, Sarkar, Sovan, Blaikley, Elizabeth J., Walker, Carol, Hulme, Lydia, Bernhard, Eric, Codlin, Sandra, Bähler, Jürg, Allshire, Robin, Whitehall, Simon, Humphrey, Timothy C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535359/
https://ncbi.nlm.nih.gov/pubmed/24909977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5091
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