ROLE OF TOLL-LIKE RECEPTORS 2 AND 4, AND THE RECEPTOR FOR ADVANCED GLYCATION END PRODUCTS IN HIGH-MOBILITY GROUP BOX 1–INDUCED INFLAMMATION IN VIVO

High-mobility group box 1 (HMGB-1) has been reported as a “late” proinflammatory mediator in sepsis. In vitro data have shown that HMGB-1 can induce activation of intracellular signaling pathways via interaction with at least three pattern recognition receptors: Toll-like receptor (TLR) 2, TLR-4, an...

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Bibliografiske detaljer
Udgivet i:Shock
Main Authors: van Zoelen, Marieke A.D., Yang, Huan, Florquin, Sandrine, Meijers, Joost C.M., Akira, Shizuo, Arnold, Bernd, Nawroth, Peter P., Bierhaus, Angelika, Tracey, Kevin J., van der Poll, Tom
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535325/
https://ncbi.nlm.nih.gov/pubmed/19218854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318186262d
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