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Preconditioning of bone marrow mesenchymal stem cells by prolyl hydroxylase inhibition enhances cell survival and angiogenesis in vitro and after transplantation into the ischemic heart of rats

INTRODUCTION: Poor cell survival and limited functional benefits have restricted the efficacy of bone marrow mesenchymal stem cells (BMSCs) in the treatment of myocardial infarction. We showed recently that hypoxia preconditioning of BMSCs and neural progenitor cells before transplantation can enhan...

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Pubblicato in:Stem Cell Res Ther
Autori principali: Liu, Xian-Bao, Wang, Jian-An, Ji, Xiao-Ya, Yu, Shan Ping, Wei, Ling
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535299/
https://ncbi.nlm.nih.gov/pubmed/25257482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt499
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