Predictability of antitumor efficacy of cetuximab plus irinotecan based on skin rash severity according to observation period in patients with metastatic colorectal cancer following failure of fluorouracil, irinotecan and oxaliplatin

The efficacy of cetuximab correlates with the severity of skin toxicity, although its onset may vary. The AIM of this retrospective study was to investigate the optimal observation period for skin rash as a predictor of the efficacy of cetuximab plus irinotecan. The subjects comprised 33 patients wi...

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Published in:Mol Clin Oncol
Main Authors: HORIE, YOSHIKI, YAMAZAKI, KENTARO, FUNAKOSHI, TARO, HAMAUCHI, SATOSHI, TANIGUCHI, HIROYA, TSUSHIMA, TAKAHIRO, TODAKA, AKIKO, MACHIDA, NOZOMU, TAKU, KEISEI, FUKUTOMI, AKIRA, ONOZAWA, YUSUKE, YASUI, HIROFUMI, MIZUKAMI, TAKURO, IZAWA, NAOKI, HIRAKAWA, MAMI, TSUDA, TAKASHI, NAKAJIMA, TAKAKO, BOKU, NARIKAZU
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534823/
https://ncbi.nlm.nih.gov/pubmed/26623045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2015.586
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