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New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity

Drug hypersensitivity reactions are an important clinical problem for both health care and industry. Recent advances in genetics have identified a number of HLA alleles associated with a range of these adverse reactions predominantly affecting the skin but also other organs, such as the liver. The a...

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Библиографические подробности
Опубликовано в: :J Allergy Clin Immunol
Главные авторы: Pirmohamed, Munir, Ostrov, David A., Park, B. Kevin
Формат: Artigo
Язык:Inglês
Опубликовано: Mosby 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534769/
https://ncbi.nlm.nih.gov/pubmed/26254050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.06.022
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