Ticagrelor potentiates adenosine-induced stimulation of neutrophil chemotaxis and phagocytosis

In the PLATO study, ticagrelor was associated with fewer pulmonary infections and subsequent deaths than clopidogrel. Neutrophils are a first-line defence against bacterial lung infection; ticagrelor inhibits cellular uptake of adenosine, a known regulator of neutrophil chemotaxis and phagocytosis....

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Detalhes bibliográficos
Publicado no:Vascul Pharmacol
Main Authors: Alsharif, Khalaf F., Thomas, Mark R., Judge, Heather M., Khan, Haroon, Prince, Lynne R., Sabroe, Ian, Ridger, Victoria C., Storey, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534709/
https://ncbi.nlm.nih.gov/pubmed/25869515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2015.02.006
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