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The Genotoxin Colibactin Is a Determinant of Virulence in Escherichia coli K1 Experimental Neonatal Systemic Infection

Escherichia coli strains expressing the K1 capsule are a major cause of sepsis and meningitis in human neonates. The development of these diseases is dependent on the expression of a range of virulence factors, many of which remain uncharacterized. Here, we show that all but 1 of 34 E. coli K1 neona...

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Библиографические подробности
Опубликовано в: :Infect Immun
Главные авторы: McCarthy, Alex J., Martin, Patricia, Cloup, Emilie, Stabler, Richard A., Oswald, Eric, Taylor, Peter W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534652/
https://ncbi.nlm.nih.gov/pubmed/26150540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00716-15
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